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Corona Vaccin

Worldwide, researchers are working on more than two hundred vaccines for the corona virus. The Netherlands has currently made agreements with six producers, through the European Commission, about the purchase of vaccines. What vaccines are these and what do we know about them?

BioNTech / Pfizer

One of the most advanced vaccines comes from pharmaceutical company Pfizer, which collaborates with BioNTech. Pfizer's shot is a so-called mRNA vaccine. This contains genetic information with which, once in the body, pieces of the corona virus can be made. These pieces cannot cause you to get COVID-19, but they do cause the immune system to produce antibodies against the coronavirus. These antibodies protect you - if it works properly - if you really encounter the corona virus later on.


Janssen

Developer Janssen's injection contains a cold virus.This virus has been modified so that you cannot become ill and, once injected, ensures that pieces of the corona virus are made in the body. With this vaccine, too, you cannot get COVID-19 from these coronavirus pieces. The pieces do ensure that you build up resistance.


Astra Zeneca

AstraZeneca's vaccine is very similar to Janssen's shot. However, a cold virus that occurs in humans has not been used, but in chimpanzees. What is striking about the study results is that the effectiveness of the vaccine increased when test subjects first received half a dose and then a full dose. The vaccine appeared to be no less than 90 percent effective in this group. It is still unclear why this method of vaccination appears to be more effective. This is being investigated further.

 

Sanofi / GSK

With the injection of the pharmaceutical company Sanofi / GSK, a piece of the corona virus is directly injected, which should lead to the production of antibodies. The final part of the study is expected to start at the end of 2020 and the pharmaceutical company hopes to deliver the first doses in the third quarter of 2021.


Cure Vac

CureVac, like Pfizer, is working on the development of an mRNA vaccine.  With this vaccine, the body is instructed to produce pieces of coronavirus, which ensure that the immune system produces antibodies. The pharmaceutical company wants to deliver the vaccinations in the second or third quarter of 2021.


Moderna

Moderna vaccine should be stored at a temperature of -20. However, it can be stored at refrigerator temperature for thirty days. The pharmaceutical company expects to be able to deliver vaccines in the EU in the first or second quarter of 2021. The vaccine, like Pfizer's, is very promising. The Moderna vaccine appears to be 94.5 percent effective, the pharmaceutical company reported on November 16. Moderna, like Pfizer and CureVac, makes an mRNA inoculation. Moderna's research is in its final phase. (24-11-2020)


 Oxford is working on converting a vaccine against new variants

Scientists at Oxford University are hard at work developing new versions of the AstraZeneca vaccine that are effective against the corona variants from South Africa, Brazil and the United Kingdom, the British newspaper Daily Telegraph reports.

According to the paper, this is happening because the current generation of covid-19 vaccines may not work against the new South African variant. The vaccine scientists are investigating how quickly they can convert their vaccine to be effective against a new variant. That could probably be done in a day or two, a source in Oxford told the newspaper.

According to a university spokesperson, it is "known that viruses are constantly changing through mutation" and we can expect many new variants to be identified by 2021.  "These changes are being closely monitored by scientists, and it is important that we remain alert to changes in the future." (21-1-2021)

 

 The AstraZeneca vaccine, the third COVID-19 vaccine

The vaccines from Pfizer-BioNTech and Moderna have already been put into use. The AstraZeneca vaccine is already in use in the United Kingdom. The European Member States have jointly ordered some 400 million vaccine doses from AstraZeneca, of which the Netherlands receives nearly 12 million.  
 
Nearly ten million doses should be delivered in the first half year. The cabinet wants to use the vaccine from AstraZeneca and Oxford University for 18 to 60-year-olds, both with and without medical problems. Some of the healthcare workers can also be vaccinated with the drug, although other vaccines are also expected for that target group. As with the Pfizer vaccine, two vaccinations are required for the injection to provide enough protection against the corona virus. The EMA hopes to reach a decision on January 29, the drug agency said in a statement. (12-01-2021)

 

Corona transformation

It started in the Lab, with the L variant in China. The first major mutation, the S variant, appeared in Asia in January 2020. The V and G variant were added in mid-January. The G variant was found in North America and Europe. This species has since mutated into variants we call GR, GH and GV. The other small species are mentioned under O variant. These variants are kept in a database by scientists so that they can continue to track mutations worldwide. (26-12-2020)

The corona virus has been transformed into 7 head variants (270+ transformation exist). Ireland announced on Friday 25-12-2020 that the mutated UK variant has also surfaced there. Currently there are confirmations from: Belgium, Denmark, Finland, France, Germany, Iceland, Italy, the Netherlands, Norway, Portugal, Spain and Sweden) and globally (Australia, Canada, Hong Kong SAR, India, Israel, Japan, Jordan, Lebanon, South Korea, Switzerland, Singapore, Iran, Brazil (09-01-2021).

 

1) The Netherlands has ordered more than 6 million doses of the Moderna vaccine, of which the first 400,000 doses are expected to be delivered this quarter, according to Minister Hugo de Jonge (Public Health). 31,000 acute care workers have been vaccinated in hospitals until Sunday 10-01-2021, the National Network reports. Acute Care (LNAZ)
2) Approximately 75,000 healthcare workers in the Netherlands have now been vaccinated. (19-01-2021)
3) In the Netherlands, 163,931 people have now received a corona vaccine. GGDs performed 106,886 injections, 40,216 injections were performed in hospitals and the counter at healthcare institutions stands at 16,829 (26-1-2021)
4)


Global vaccination 

Global vaccination 
a) Global vaccination won't begin until the second (Q2) or third quarter (Q3) of 2021. Problems getting enough raw materials for Pfizer / biotechnologist BioNTech. Update: Work is currently being done on a way of making the doses easier to store. Now the vaccine has to be stored at a temperature of -70 degrees. CEO Sahin expects that the next version of the vaccine can also be stored at higher temperatures. That version should be ready by the end of the summer 2021. (01-01-2021)
b) It's not yet known with certainty whether the corona vaccine that AstraZeneca and the University of Oxford are developing is effective in people over 55 years old.
c) British and Russian pharmaceutical companies want to merge vaccines.
d) New variant of coronavirus identified in England. A new mutation by Feb. 2021.
e) People with a history of severe allergic reactions to medicines, food or vaccinations should not receive a Pfizer / BioNTech vaccination for the time being.
f) The first corona vaccines from BioNTech and Pfizer will be distributed to all EU Member States simultaneously, according to EU Commissioner Stella Kyriakides (Public Health). The start of vaccination in the Netherlands (2.5 million vaccines, 1.25 million pepole) will remain on 6 January 2021, intended for nurses and elderly people.


The Dutch population is divided into groups

Change of plan: First, it is the turn of the acute care workers: personnel in ambulances, the emergency department and the IC and Covid wards. So that's part of the original group 4 and 5. 
The GPs (doctors) are also given priority, it was decided recently. They will not be added to the first group, which is vaccinated with the Pfizer vaccine, but are the first to be vaccinated with the Moderna vaccine. This is expected to be available at the end of February 2020 after approval by the EMA. (04-01-2020)
Group 1: A. Nursing home residents and people with an intellectual disability in institutions.
B. Care employees of nursing homes, care for the disabled, community nursing and WMO support.
Group 2: People over sixty with and without a medical indication, the oldest age group being the first.
Group 3: People under sixty with a medical indication.
Group 4: The care workers of the people in groups 2 and 3.
Group 5: Healthcare workers who are in direct contact with covid patients.
Group 6: Other healthcare workers.
Group 7: People aged 18-60.



Latest news


Moderna will be distributed across the country

From 11-01-2021, the corona vaccine from the American company Moderna will be distributed across the country. The European Medicines Agency (EMA) approved Moderna last Wednesday.  After the BioNTech / Pfizer vaccine, this is the second corona vaccine authorized in the EU. It is still unclear when the first vaccines will be administered. The Netherlands has ordered more than 6 million doses of the Moderna vaccine, of which the first 400,000 doses are expected to be delivered this quarter, said Hugo de Jonge.

 

Pfizer vaccine appears to be effective against mutation

British and South African variants Pfizer / BioNTech vaccine also appears to be effective against mutation in the highly contagious variants of the coronavirus found in the UK and  Touring South Africa. The company says this based on a laboratory study it carried out together with scientists from the University of Texas. (07-01-2021)

 

Approval for Moderna

The European Medicines Agency (EMA) has approved a vaccine against COVID-19 for the second time, it was announced on Wednesday. The vaccine was developed by the American Moderna and can soon be used in the European Union, just like the vaccine from Pfizer. The corona vaccine is expected to protect 94 percent of vaccinees against COVID-19. The Netherlands has signed a contract with Moderna through the European Commission for 6.2 million doses. Because everyone needs two doses, it can vaccinate 3.1 million people against COVID-19. Moderna is expected to deliver 390,000 doses in the first quarter of this year. (06-01-2021)


Three quarters of the Dutch are willing to be vaccinated

More Dutch people are willing to get vaccinated against the corona virus.  Research agency Ipsos questioned Dutch people last week on behalf of the NOS and came to the conclusion that the willingness to vaccinate has increased to 75 percent. (05-01-2021)

 

Israel also approves Moderna vaccine 

The corona vaccine of the American pharmaceutical company Moderna can be used in Israel.  It is the third country to officially approve the vaccine after the United States and Canada.  The European Medicines Agency (EMA) may approve the vaccine on Wednesday. Moderna plans to produce at least 600 million vaccines this year.  Israel has ordered six million doses. The vaccination campaign in the country of nine million inhabitants is proceeding extremely well.  In just over two weeks, 1.37 million people have been vaccinated with the first dose of the US-German vaccine from Pfizer / BioNTech. (05-01-2021).

 

Indonesia begins on January 13, 2021 with Chinese vaccine on a large scale

On January 13, Indonesia starts a major vaccination campaign with the Chinese vaccine from Sinovac Biotech. The first to be vaccinated is President Joko Widodo. The country wants to start vaccinating 1.3 million people who are active in healthcare. (Previously, a test with the Chinese vaccine achieved only 50% result in Brazil).

In Indonesia, 772,000 people have been tested positive for the corona virus.  Nearly 23,000 COVID-19 patients died from the effects of the virus. (05-01-2021)


Pharmacists and regulator: vaccine efficacy in case of postponement of second injection not proven

Vaccine developers Pfizer and BioNTech warn that there is no evidence that their corona vaccine offers sufficient protection if the second injection is delayed.  Several countries choose or are considering giving the second injection not within three weeks, but only later. Pfizer and BioNTech's corona vaccine should be administered twice for maximum protection. The manufacturers use an interval of three weeks. That is also the period that was adhered to when testing the vaccine.  "There is no data showing that protection will last beyond the 21-day period," say the manufacturers. (05-01-2021)

 

First vaccination with Oxford / AstrazZeneca vaccine In UK

Vaccination has started with the vaccine from Oxford University and pharmaceutical company AstraZeneca.  The first Briton to be injected with the drug outside the test period was 82-year-old kidney patient Brian Pinker.  He received it in his hometown of Oxford, several hundred yards from where it was developed. (04-01-2021)

 

New Pfizer in 2021

Work is currently being done on a way of making the doses easier to store. Now the vaccine has to be stored at a temperature of -70 degrees. CEO Sahin expects that the next version of the vaccine can also be stored at higher temperatures.That version should be ready by the end of the summer 2021. (01-01-2021)


Britons are already being vaccinated 

With the vaccine from Pfizer and BioNTech. But a crucial advantage of the AstraZeneca vaccine is that it can be kept in normal refrigerators. It can therefore be more easily used in nursing homes or at GP stations, for example. The UK medicines authority has approved the use of the corona vaccine from UK pharmaceutical company AstraZeneca and the University of Oxford. (30-12-2020)

 

RIVM: 'vaccination certificate' March 2021

Cann only be downloaded at the end of March, not at the end of January. From the end of March 2021, it will be possible to view your own data about your vaccination against the corona virus, the RIVM reports.  You can log in with DigiD via a website. The data can be downloaded to serve as proof of, for example. (04-01-2021)

 

Pharmaceutical Sanofi wrote on its own page

That scientists have to return to the drawing board due to "disappointing research results". The drug is said to induce a too small immune response in people over 50. The vaccine is said to be sufficiently effective in people between the ages of 18 and 49. (11-12-2020)

 

British and Russian pharmaceutical companies want to merge vaccines

British pharmaceutical company AstraZeneca and Russian authorities want to investigate whether their vaccines can be combined in development, researchers report Friday 11 December 2020.

The Russian Sputnik V vaccine is said to have an effectiveness of more than 90 percent, while the AstraZeneca vaccine is effective in at least 70 percent of all cases. By combining both drugs, the pharmaceuticals hope for an even higher degree of effectiveness. Some tests were to be carried out before the end of the year 2020.

The head of Russia's sovereign wealth fund, Kirill Dmitriev, suspects that the collaboration of scientists will become "crucial" to bring the pandemic to an end. (11-12-2020)

 

Russia, first country, vaccinating the population against the corona virus

Vaccination centers have been opened in Moscow, where teachers and people working in the healthcare sector can receive an injection. Russia claims it has an effectiveness of more than 90 percent, but the WHO health organization has yet to investigate that claim.
The vaccine Spoetnik V costs 16 euros per dose, but the Russian government vaccinates citizens for free.  From the beginning of next year, people will need to be vaccinated across the country. In total, there would be two million doses in stock, Health Minister Mikhail Murashko said last week. With a population of more than 144 million Russians, that is nowhere near enough.(5-12-2020)

 

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